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The gap between the eligible population and the treated one is shaped by cost, insurance coverage, supply, and personal preference

The risk of renal adverse reactions was increased in patients with a history of renal impairment (the weight management trials included 65 patients with a history of moderate or severe renal impairment at baseline), and occurred more frequently during dose titration

Depending on individual glycaemic response and tolerability, the dose may be further increased to 1 mg once weekly after at least four weeks at the 0.5 mg dose

Resveratrol induces glutathione synthesis and protects against oxidative stress